Autor: Colin R. Dunstan
ISBN-13: 9783319379715
Veröffentl: 10.09.2016
Einband: Previously published in hardcover
Seiten: 260
Gewicht: 398 g
Format: 235x155x14 mm
Sprache: Englisch

A Tissue Regeneration Approach to Bone and Cartilage Repair

 Previously published in hardcover
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Reviews exhaustively the key recent research regarding bioactive biomaterials and the mechanisms through which they influence the local bone and joint environment to induce tissue repair and regeneration
Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration.

Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues.

This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.
Editiert von: Colin R. Dunstan, Vicki Rosen, Hala Zreiqat
Hala Zreiqat is expert in developing biomaterials for bone/cartilage tissue repair and regeneration and the in vivo/in vitro assessment of cell-biomaterial interaction.
Colin Dunstan is an expert in bone cell biology and the interrelationships between bone cells and their microenvironment.

Vicki Rosen is an expert is studying the physiological roles that bone morphogenetic proteins (BMPs) play in the development, maintenance, and repair of musculoskeletal tissues (bone, cartilage, tendon, ligament, meniscus, muscle).

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Autor: Colin R. Dunstan
ISBN-13:: 9783319379715
ISBN: 3319379712
Erscheinungsjahr: 10.09.2016
Verlag: Springer International Publishing
Gewicht: 398g
Seiten: 260
Sprache: Englisch
Auflage Softcover reprint of the original 1st ed. 2015
Sonstiges: Taschenbuch, 235x155x14 mm