Autor: Natalia Maltsev
ISBN-13: 9781461487777
Veröffentl: 01.12.2013
Einband: Book w. online files/update
Seiten: 122
Gewicht: 391 g
Format: 246x161x15 mm
Sprache: Englisch

Systems Analysis of Human Multigene Disorders

799, Advances in Experimental Medicine and Biology

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This book presents bioinformatics approaches for systems-level analysis of biological systems and prediction of causative multidimensional patterns of inheritance characteristic of multigene disorders.
InhaltsangabeWellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine.- Characterizing Multi-omic Data in Systems Biology.- High-throughput Translational Medicine: Challenges and Solutions.- Computational approaches for human disease gene prediction and ranking.- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization.- Index.
Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine.- Characterizing Multi-omic Data in Systems Biology.- High-throughput Translational Medicine: Challenges and Solutions.- Computational approaches for human disease gene prediction and ranking.- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization.- Index.
Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.
Editiert von: Natalia Maltsev, Andrey Rzhetsky, Conrad T. Gilliam
InhaltsangabeWellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine.- Characterizing Multi-omic Data in Systems Biology.- High-throughput Translational Medicine: Challenges and Solutions.- Computational approaches for human disease gene prediction and ranking.- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization.- Index.

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Autor: Natalia Maltsev
ISBN-13:: 9781461487777
ISBN: 1461487773
Erscheinungsjahr: 01.12.2013
Verlag: Springer-Verlag GmbH
Gewicht: 391g
Seiten: 122
Sprache: Englisch
Sonstiges: Buch, 246x161x15 mm, 12 illus., 10 illus. in color. With online files/update., 2 schwarz-weiße und 10 farbige Abbildungen